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Updated: Apr 16, 2026
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Imaging of Sarcoidosis
Mario Silva1, Hilario Nunes, Dominique Valeyre
1Section of Radiology, Department of Surgical Sciences, University of Parma, Parma, Italy, mariosilvamed@gmail.com.
Diagnostic imaging is crucial for diagnosing and managing sarcoidosis. Various techniques like CT and HRCT assess thoracic and extra-thoracic involvement, aiding prognostication and complication detection.
Area of Science:
- Radiology
- Pulmonology
- Immunology
Background:
- Sarcoidosis diagnosis and management rely heavily on imaging.
- Imaging assesses both thoracic and extra-thoracic sarcoidosis involvement.
Purpose of the Study:
- To review the role of diagnostic imaging in sarcoidosis diagnosis and follow-up.
- To highlight the utility of various imaging modalities in sarcoidosis.
Main Methods:
- Review of current literature on diagnostic imaging in sarcoidosis.
- Discussion of chest radiography, computed tomography (CT), high-resolution CT (HRCT), radionuclide imaging, and magnetic resonance (MR).
Main Results:
- Chest radiography is a cornerstone since 1961, with CT as the reference standard for mediastinal and pulmonary findings.
- HRCT excels in detecting subtle parenchymal involvement and differentiating reversible/irreversible lung disease.
- Radionuclide imaging and MR provide insights into disease activity and myocardial involvement, respectively.
Conclusions:
- Diagnostic imaging is essential for sarcoidosis diagnosis, staging, and management.
- CT is vital for detecting complications, though its role in asymptomatic patient follow-up is debated.
- Imaging modalities offer complementary information for comprehensive sarcoidosis assessment.
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