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Updated: Apr 16, 2026

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
[Aspects of encephalopathy in oncologic patients after chemotherapy]
N B Kholodova1, V M Sotnikov1, N Iu Dobrovol'skaia1
1FGBU 'Rossiĭskiĭ nauchnyĭ tsentr rentgenoradiologii' Minzdrava Rossii, Moskva.
Objective:
To study clinical presentations and neuroimaging results in post chemotherapy encephalopathy.
Material And Methods:
We examined 27 patients with cancer after chemotherapy (n=16) or chemoradiation (n=11).
Results And Conclusion:
All patients complained of memory impairment, sluggish mentality, moderate headache, fatigue, sleep disorder, irritability. Their neurologic status included different organic symptoms. Post chemotherapy encephalopathy is characterized by the combination of severe cerebral asthenia and different organic neurologic symptoms with moderate cephalgic syndrome. MRT showed single and multiple loci of gliosis in the white matter.
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