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Author Spotlight: Advancing Personalized Medicine in Ovarian Cancer

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Published on: February 23, 2024

Making personalized medicine more affordable.

Naomi Aronson¹

¹Office of Clinical Affairs, Blue Cross and Blue Shield Association, Chicago, Illinois.

Annals of the New York Academy of Sciences

|March 3, 2015

Summary

Precision medicine addresses patient heterogeneity but faces cost challenges. Ensuring access and sustainability requires stakeholder stewardship for this evolving field.

Keywords:

biomedical costs economics genetic testing individualized medicine patient-centered technology assessment

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Area of Science:

Biomedical Sciences
Genomics
Healthcare Economics

Background:

Precision medicine aims to tailor treatments to individual patients, addressing issues like treatment response variability and potential harms.
The heterogeneity of patient populations and the 'tyranny of the mean' present significant challenges in clinical care.
Rising healthcare costs necessitate a re-evaluation of treatment efficiency and economic sustainability.

Purpose of the Study:

To explore the potential of precision medicine in overcoming clinical care challenges.
To analyze the economic implications, including costs and benefits, of implementing precision medicine.
To discuss the factors influencing the affordability and accessibility of precision medicine.

Main Methods:

Conceptual analysis of precision medicine's role in clinical practice.
Review of economic factors related to genetic testing and treatment development.
Discussion of healthcare system affordability and stakeholder responsibilities.

Main Results:

Precision medicine offers solutions for patient heterogeneity but introduces new cost considerations.
Decreasing costs of next-generation sequencing contrast with potential expenses from false positives and incidental findings.
The overall affordability of precision medicine is linked to broader healthcare system economics.

Conclusions:

Precision medicine's success is contingent on addressing its economic viability.
Stakeholder collaboration is crucial for ensuring equitable access and long-term sustainability.
Balancing innovation with affordability is key to realizing precision medicine's full potential.