Relation between birth weight and weight and height at the age of 2 in children born preterm

Gayle Olson1, Steven J Weiner2, Dwight J Rouse3

  • 1Department of Obstetrics and Gynecology, University of Texas Medical Branch Galveston, Galveston, Texas.

Insights

Customized birth weight percentile is a minor factor in preterm infants' weight at 2 years. This study found a weak association between fetal growth and later weight and height outcomes.

Area of Science:

  • Pediatrics
  • Neonatology
  • Growth and Development

Background:

  • Assessing fetal growth and its impact on long-term outcomes in preterm infants is crucial.
  • Traditional birth weight standards may not accurately reflect individual growth potential.

Purpose of the Study:

  • To evaluate the association between customized fetal growth percentiles and weight at 2 years in preterm infants.
  • To determine if customized birth weight percentiles predict weight and height at 2 years.

Main Methods:

  • Secondary analysis of a multicenter trial with 2-year follow-up of preterm infants.
  • Calculation of customized birth weight percentiles using the Gardosi model.
  • Regression analysis and z-score comparisons to assess the relationship between customized percentile and 2-year weight/height.

Main Results:

  • Lower weight and height z-scores at 2 years were observed in preterm infants with birth weight below the 10th customized percentile compared to those at or above it.
  • These differences persisted after adjusting for maternal education.
  • While positive relationships existed between customized birth weight percentile and 2-year growth, they were weak.

Conclusions:

  • Customized birth weight percentile plays a minor role in determining weight at 2 years for preterm infants.
  • Further research may be needed to identify stronger predictors of growth in this population.
Abstract

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