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Updated: Apr 16, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Prevalence of Venoatrial Compression by Lymphadenopathy in Sarcoidosis
Matthieu Gomes1, Sofiane Bendaoud, Lidwine Wemeau-Stervinou
1*Department of Thoracic Imaging, Hospital Calmette (EA 2694) †Department of Pulmonology, Centre of Rare Pulmonary Diseases ‡Department of Biostatistics (EA 2694), CHRU et Université de Lille 2 Nord de France, Lille, France.
Purpose:
The purpose of the study was to evaluate the prevalence of compressive lymphadenopathy on pulmonary veins (PV) and left atrium (LA) in patients with sarcoidosis.
Materials And Methods:
A total of 101 consecutive patients underwent a chest computed tomography angiographic examination with specific analysis of: (a) 3 nodal stations (ie, 7, 8, and 9 stations) for detection of LA compression; (b) 2 nodal stations (ie, 10 and 11 right and left stations) for detection of PV compression.
Results:
Lymphadenopathy was present in 64 patients (64/101; 63.4%) with computed tomography features of venoatrial compression in 17 patients (17/101; 16.8%). This subgroup included 10 patients with LA compression alone (10/64; 15.6%), 6 patients with PV compression alone (6/64; 9.4%), and 1 patient with both (1/64; 1.5%). The mean diameter of enlarged lymph nodes compressing the LA and PVs was 3.18 ± 0.73 cm (range: 2.1 to 4.4 cm) and 1.9 ± 0.45 cm (range: 1 to 2.9 cm), respectively. PV compression was depicted in a total of 7 patients (7/101; 6.9%), observed as a unilateral (n = 5) or bilateral (n = 2) finding, with a mean number of 3.0 PVs compressed per patient (range: 1 to 7). A total of 10 venous sections showed features of compression, at the level of a lobar confluence (n = 6) or individual segmental veins (V6; n = 4), with a mean reduction in the venous cross-sectional area of 51.09% ± 12.85% (median: 50.06%). Nonfibrotic lung infiltration associated with sarcoidosis was observed in 88.2% of patients with compressive lymphadenopathy (15/17).
Conclusions:
The prevalence of venoatrial compression in sarcoidosis is 16.8% in the studied population.
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