[Quantitative analysis of connective tissue matrix structure during myocardial remodeling]

A new approach is proposed to quantify a contribution of connective tissue matrix to the myocardial structure. Also we introduced a new morphometrical criterion to estimate mean thickness of connective tissue fibers by histological section of isolated myocardial samples. The approach allows of correlating structural and functional changes in cardiac tissue by myocardium remodeling during pathology, age-related changes.