Related Experiment Video
Updated: Apr 16, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
[A case of stromal sarcoma with multiple local recurrences]
Eriko Murakami1, Katsuhisa Enomoto, Kenichi Sakurai
1Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
This case study highlights a rare breast stromal sarcoma in a 53-year-old woman. Despite multiple surgical interventions, the patient experienced recurrent lesions, underscoring the challenges in managing this aggressive tumor.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Breast stromal sarcoma is a rare malignant tumor originating from the connective tissue of the breast.
- This tumor type presents diagnostic and therapeutic challenges due to its rarity and potential for aggressive behavior.
Observation:
- A 53-year-old woman presented with a palpable right breast lump that progressively enlarged over six months.
- Imaging revealed a breast lesion; biopsy confirmed stromal sarcoma.
- The patient underwent multiple surgical interventions including mastectomy and lumpectomy due to recurrent lesions within months.
Findings:
- Despite serial surgical excisions, the patient experienced rapid and multiple recurrences of breast stromal sarcoma.
- Post-surgical examination of the breast stump showed no residual lesions or recurrence.
- Systemic evaluation ruled out metastasis to distant organs.
Implications:
- This case underscores the aggressive nature and high recurrence rate of breast stromal sarcoma.
- Surgical excision, while necessary, may not be curative for this rare malignancy.
- Further research into effective therapeutic strategies for breast stromal sarcoma is warranted.
More Related Videos
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
09:21Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019