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Updated: Apr 16, 2026
06:46
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
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[Six synchronous primary cancers - a case report]
Tadayoshi Hashimoto1, Hirokazu Taniguchi, Atsushi Takeno
1Dept. of Surgery, Kansai Rosai Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|March 4, 2015
Summary
This case study details a patient with multiple gastrointestinal and lung cancers. Successful multi-modal treatment involving surgery, chemotherapy, and chemoradiotherapy led to a good outcome without recurrence.
Area of Science:
- Gastroenterology and Oncology
- Surgical Oncology
- Pulmonary Medicine
Background:
- A 60-year-old male presented with dysphagia, initially diagnosed with esophageal and gastric cancers.
- Diagnostic workup revealed additional lesions in the duodenum, transverse colon, right vocal cord, and right lung.
Observation:
- Endoscopic and laryngoscopic examinations identified tumors and vocal cord erosion.
- Computed tomography (CT) confirmed a lung nodule.
- Biopsies confirmed various malignancies including esophageal cancer, gastric cancer, primary pulmonary adenocarcinoma, and early-stage lesions in the duodenum and colon.
Findings:
- The patient underwent neoadjuvant chemotherapy (5-fluorouracil, cisplatin, Adriamycin regimen).
- Surgical interventions included subtotal esophagectomy, total gastrectomy, and lung resection.
- Pathological staging confirmed esophageal cancer (Stage III), gastric cancer (Stage IIA), and pulmonary adenocarcinoma (Stage IIA).
Implications:
- Post-operative chemoradiotherapy (5-fluorouracil plus cisplatin) was administered.
- The patient achieved a favorable outcome with no evidence of recurrence 6 months post-operation.
- This case highlights the successful management of synchronous multi-organ malignancies through a comprehensive treatment strategy.
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