4DCT Simulation With Synchronized Contrast Injection in Liver SBRT Patients

Area of Science:

• Radiation Oncology
• Medical Imaging
• Oncology

Background:

• Stereotactic body radiotherapy for liver metastases faces challenges due to respiratory motion.
• Poor visibility without intravenous contrast complicates accurate target delineation.

Purpose of the Study:

• To describe a novel computed tomography (CT) simulation process.
• To integrate timed intravenous contrast for improved target delineation in liver metastases radiotherapy.

Main Methods:

• The technique involves two 4-dimensional CT (4DCT) scans.
• The first 4DCT scan focuses on the tumor region for optimized contrast timing.
• The second 4DCT scan covers a larger volume for treatment planning and verification.

Main Results:

• This dual 4DCT approach allows optimal visualization of liver metastases across all breathing phases.
• It enables simultaneous acquisition of data suitable for planning and patient setup.
• The method overcomes uncertainty in target delineation.

Conclusions:

• The described simulation technique enhances target definition for liver metastases treatment.
• This non-invasive approach improves accuracy in radiotherapy planning.