Related Experiment Video
Updated: Apr 16, 2026

Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
Published on: September 11, 2017
Order from the order: how a spatiotemporal genetic program is encoded in a 2-D genetic map of the bacterial
Georgi Muskhelishvili1, Andrew Travers
1School of Engineering and Science, Jacobs University Bremen, Bremen, Germany.
Abstract:
In this article, we sketch out a holistic methodology used for exploring how the genetic program is encoded in a 2-D genetic map of a bacterial chromosome. We argue that the major problem resides in the conceptual integration of the two logically distinct types of information encoded in the chiral double-helical DNA polymer. This integration is accomplished by mapping the genetic function on the genomic sequence organisation and therefore is potentially applicable to any chromosome. The vast generalisation achieved by this approach necessarily ignores exquisite details, yet it is fundamental in providing comprehensive methodology for exploring the role of the DNA sequence organisation in harnessing genetic information and sustaining biological order.
Related Concept Videos
Coordination of Gene Expression Processes in Bacteria
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Cytoskeletal Proteins in Bacteria
Karyotyping
Evolution of Microbial Genome
DNA as a Genetic Template

