Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cholera01:25

Cholera

98
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
98
Cohesins02:20

Cohesins

5.9K
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and meiosis. In mitosis, all cohesin complexes present on the chromosomes are removed before the start of the anaphase stage.
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of...
5.9K
Separation of Sister Chromatids02:17

Separation of Sister Chromatids

4.8K
At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
4.8K
Separation of Sister Chromatids02:17

Separation of Sister Chromatids

2.7K
2.7K
Condensins02:15

Condensins

5.0K
Condensins are large protein complexes that use ATP to fuel the assembly of chromosomes during mitosis. They transform the tangled, shapeless mass of post-interphase DNA into individualized chromosomes by compacting, organizing, and segregating chromosomal DNA.
The plant and animal cells contain two types of condensin complexes—condensin I and condensin II. Both complexes have five subunits: two SMC (Structural Maintenance of Chromosomes) subunits, a kleisin subunit, and two HEAT-repeat...
5.0K
Meiosis II02:02

Meiosis II

52.0K
Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
52.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative ASCL1 interactome analysis reveals CDK2-Cyclin A2 as suppressors of differentiation in MYCN-amplified neuroblastoma.

Molecular cancer research : MCR·2026
Same author

Development of a Central Sensitization Inventory short form using data from twenty-three countries.

The journal of pain·2026
Same author

Alternative Methods in Microbial QC: Evaluating the Use of the ATCC MicroQuant™ as a Ready-To-Use Commercial Reference Microorganism Preparation on the Growth Direct® System: Poster Presented at PDA Microbiology Conference 2025.

PDA journal of pharmaceutical science and technology·2026
Same author

A novel membrane stress response that blocks chromosomal replication by targeting the DnaA initiator via the ClpP protease.

Journal of bacteriology·2025
Same author

FBXO22 deficiency defines a pleiotropic syndrome of growth restriction and multi-system anomalies associated with a unique epigenetic signature.

American journal of human genetics·2025
Same author

Hepatic hyperechoic lesion in a young, healthy man.

Proceedings (Baylor University. Medical Center)·2024

Related Experiment Video

Updated: Apr 16, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

11.6K

Chromosome segregation in Vibrio cholerae.

Revathy Ramachandran1, Jyoti Jha, Dhruba K Chattoraj

  • 1Laboratory of Biochemistry and Molecular Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Md., USA.

Journal of Molecular Microbiology and Biotechnology
|March 4, 2015
PubMed
Summary

This review explores chromosome segregation in Vibrio cholerae, a bacterium with a unique divided genome. We examine its segregation mechanisms and compare them to other bacteria, highlighting open questions in cell biology research.

More Related Videos

TransFLP — A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination
12:13

TransFLP — A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination

Published on: October 8, 2012

15.5K
Coincubation Assay for Quantifying Competitive Interactions between Vibrio fischeri Isolates
07:43

Coincubation Assay for Quantifying Competitive Interactions between Vibrio fischeri Isolates

Published on: July 22, 2019

8.8K

Related Experiment Videos

Last Updated: Apr 16, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

11.6K
TransFLP — A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination
12:13

TransFLP — A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination

Published on: October 8, 2012

15.5K
Coincubation Assay for Quantifying Competitive Interactions between Vibrio fischeri Isolates
07:43

Coincubation Assay for Quantifying Competitive Interactions between Vibrio fischeri Isolates

Published on: July 22, 2019

8.8K

Area of Science:

  • Cell Biology
  • Microbiology
  • Genetics

Background:

  • Chromosome segregation is a fundamental process in cell division.
  • Vibrio cholerae possesses a unique divided genome, a rare trait among bacteria.
  • Understanding bacterial chromosome segregation is crucial for cell biology.

Purpose of the Study:

  • To review current knowledge on chromosome segregation in Vibrio cholerae.
  • To compare Vibrio cholerae's segregation mechanisms with other bacteria.
  • To identify remaining questions in bacterial chromosome segregation.

Main Methods:

  • Primarily based on fluorescence microscopy experiments.
  • Comparative analysis of segregation mechanisms across different bacterial species.

Main Results:

  • Vibrio cholerae exhibits distinct chromosome segregation due to its divided genome.
  • Insights into the eukaryotic-like genome organization in bacteria.

Conclusions:

  • Vibrio cholerae serves as a model for studying unique bacterial chromosome segregation.
  • Further research is needed to fully elucidate bacterial chromosome segregation mechanisms.