Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Pituitary Gland01:17

The Pituitary Gland

16.8K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
16.8K
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

16.6K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
16.6K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

3.5K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
3.5K
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

4.2K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
4.2K
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

8.1K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
8.1K
Structures of the Endocrine System00:59

Structures of the Endocrine System

17.9K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
17.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cancer Risk in Acromegaly: Reassessing the Evidence and Impact of Biochemical Control.

The Journal of clinical endocrinology and metabolism·2026
Same author

Impact of acromegaly subtypes on survival: results from a large multicenter cohort.

Journal of the Endocrine Society·2026
Same author

Consensus on acromegaly complications: an update.

Pituitary·2026
Same author

Pathogenesis of nonfamilial somatotroph adenomas.

The Journal of clinical endocrinology and metabolism·2026
Same author

The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.

British journal of pharmacology·2025
Same author

Patient perceptions of pituitary incidentaloma diagnosis and follow-up: a Pituitary Society international patient survey.

Pituitary·2025

Related Experiment Video

Updated: Apr 16, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

20.2K

Pituitary tumors.

Shlomo Melmed1

  • 1Pituitary Center, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Room 2015, Los Angeles, CA 90048, USA.

Endocrinology and Metabolism Clinics of North America
|March 4, 2015
PubMed
Summary
This summary is machine-generated.

Pituitary tumors are common brain neoplasms that are benign. Their growth involves cell cycle disruptions and growth factors, with hormone secretions influencing clinical presentation.

Keywords:
Hormone gene productsNeoplasmPituitaryTumor

More Related Videos

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

4.8K
Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy
03:13

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

1.6K

Related Experiment Videos

Last Updated: Apr 16, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

20.2K
Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

4.8K
Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy
03:13

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

1.6K

Area of Science:

  • Neuro-oncology
  • Endocrinology
  • Cell Biology

Background:

  • Pituitary tumors are frequent intracranial neoplasms, consistently benign.
  • Unlike many cancers, they lack classic oncogene mutations.
  • Pathogenesis involves cell cycle dysregulation and growth factor signaling.

Purpose of the Study:

  • To review the pathogenesis and clinical features of pituitary tumors.
  • To highlight the role of cell cycle control and growth factors.
  • To emphasize the impact of secreted hormones on clinical presentation.

Main Methods:

  • Literature review of pituitary tumor research.
  • Analysis of genetic and molecular pathways.
  • Correlation of tumor characteristics with clinical manifestations.

Main Results:

  • Pituitary tumors are benign intracranial neoplasms.
  • Cell cycle control disruption and growth factor signaling are key to their development.
  • Clinical features are dictated by specific hormone gene products.

Conclusions:

  • Pituitary tumor development is linked to cell cycle and growth factor pathways.
  • Hormone secretion is a critical determinant of pituitary tumor clinical behavior.