Management of cardiogenic shock
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Updated: Apr 16, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Holger Thiele1, E Magnus Ohman2, Steffen Desch3
1Medical Clinic II (Cardiology/Angiology/Intensive Care Medicine), University Heart Centre Luebeck, University Hospital Schleswig-Holstein, Ratzeburger Allee 160, Luebeck 23538, Germany holger.thiele@uksh.de.
Insights
Cardiogenic shock (CS) management in acute myocardial infarction (AMI) focuses on evidence-based revascularization and intensive care. This review details optimal treatments, including mechanical support, to reduce high mortality rates.
Area of Science:
- Cardiology
- Intensive Care Medicine
Background:
- Cardiogenic shock (CS) is a major cause of death in acute myocardial infarction (AMI).
- Despite advances, CS mortality remains high (40-50%), necessitating optimized management strategies.
- Current treatments like catecholamines and intra-aortic balloon pumping (IABP) have limited evidence, except for early revascularization.
Purpose of the Study:
- To provide an updated, evidence-based review on managing CS complicating AMI.
- To focus on revascularization techniques, intensive care unit (ICU) treatment, and mechanical support devices.
Main Methods:
- Review of current literature on cardiogenic shock management in acute myocardial infarction.
- Emphasis on evidence-based revascularization strategies.
- Discussion of intensive care unit protocols and mechanical circulatory support.
Main Results:
- Early revascularization is crucial for improving outcomes in CS patients.
- Limited evidence supports the efficacy of IABP in CS.
- Comprehensive ICU management, including ventilation and transfusion, is vital.
Conclusions:
- Optimized management of CS in AMI requires a multi-faceted approach.
- Evidence-based revascularization and advanced critical care are key to reducing mortality.
- Mechanical support devices play a role in select CS patients.
Abstract:
Cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction although mortality could be reduced from formerly ∼80% to 40-50%. In addition to percutaneous coronary intervention or coronary artery bypass grafting, catecholamines, fluids, intraaortic balloon pumping (IABP), and also active assist devices are widely used for CS management. However, there is only limited evidence for any of the above treatments except for early revascularization and the relative ineffectiveness of IABP. This updated review will therefore outline the management of CS complicating acute myocardial infarction with major focus on evidence-based revascularization techniques, intensive care unit treatment including ventilation, transfusion regimens, adjunctive medication, and mechanical support devices.
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