Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

463
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
463
The Arch of Aorta01:10

The Arch of Aorta

2.4K
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
2.4K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

637
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
637

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delayed identification and treatment of a cervicomedullary spinal vascular lesion following angiogram-negative, high-grade subarachnoid hemorrhage: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Management of pseudotumor cerebri syndrome in acute promyelocytic leukemia: use of a lumboperitoneal shunt to facilitate continued ATRA therapy - a case report.

Annals of hematology·2026
Same author

Prehospital Detection of Large Vessel Occlusion and Intracerebral Hemorrhage Using a Dual-Biomarker Point-of-Care Test.

Stroke (Hoboken, N.J.)·2026
Same author

Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-analysis.

AJNR. American journal of neuroradiology·2026
Same author

Case Report: transcavernous sinus resection of parotid carcinoma with perineural invasion to Meckel's cave and cavernous sinus.

Frontiers in oncology·2026
Same author

The suprabulbar approach for jugular fossa schwannomas: case series and technical nuances.

Journal of neurosurgery·2026

Related Experiment Video

Updated: Apr 16, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
18:50

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

14.2K

Morphological parameters associated with middle cerebral artery aneurysms.

Anil Can1, Allen L Ho, Ruben Dammers

  • 1*Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; ‡Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands.

Neurosurgery
|March 4, 2015
PubMed
Summary

Smaller middle cerebral artery (MCA) parent artery diameter and wider daughter-to-daughter branch angles are linked to MCA aneurysms. These measurements may help assess aneurysm risk.

More Related Videos

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
07:43

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion

Published on: February 22, 2013

15.5K
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

2.6K

Related Experiment Videos

Last Updated: Apr 16, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
18:50

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

14.2K
Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
07:43

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion

Published on: February 22, 2013

15.5K
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

2.6K

Area of Science:

  • Neuroimaging
  • Vascular Anatomy
  • Biomedical Engineering

Background:

  • Morphological factors significantly influence blood flow dynamics within the middle cerebral artery (MCA).
  • Understanding these anatomical contributions is crucial for identifying risks associated with cerebrovascular diseases.

Purpose of the Study:

  • To pinpoint specific image-based morphological parameters correlated with the existence of middle cerebral artery (MCA) aneurysms.
  • To establish quantitative imaging biomarkers for MCA aneurysm risk stratification.

Main Methods:

  • Utilized Slicer, open-source software, to analyze 3D vascular models from 110 patients with and without MCA bifurcation aneurysms.
  • Examined parent and daughter vessel dimensions and angles at the MCA bifurcation.
  • Employed control groups (contralateral side and patients without aneurysms) to mitigate confounding factors.

Main Results:

  • Multivariate analysis identified a smaller parent artery diameter as a significant predictor (OR 0.20-0.23, P < .01) of MCA aneurysms.
  • A larger daughter-to-daughter branch angle was also strongly associated with aneurysm presence (OR 1.01-1.02, P = .04).

Conclusions:

  • Reduced parent artery diameter and increased daughter-to-daughter branch angles are key morphological indicators of MCA aneurysm formation.
  • These easily quantifiable parameters offer objective metrics for assessing aneurysm risk and guiding clinical management in susceptible individuals.