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Biological therapy in acute severe ulcerative colitis: Indian experience

Ajit Sood, Vandana Midha, Arshdeep Singh

    Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
    |March 5, 2015
    PubMed

    Biologicals have a well established role as rescue therapy in management of steroid refractory cases of Ulcerative colitis and Crohn's disease. However, high cost and potential risk of infections like tuberculosis limits their use in developing countries. As there is paucity of data on the use of various biological agents from developing countries like India, we are reporting the limited Indian experience with the available agents. Infliximab has been used as a rescue therapy for severe refractory Ulcerative colitis while other agents have been used as a part of multicentre clinical trials.

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