Related Experiment Video

Updated: Apr 16, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

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Four-Dimensional Speckle Tracking Echocardiography in Patients with Hypertrophic Cardiomyopathy

Kadriye Orta Kilickesmez1, Onur Baydar1, Cem Bostan1

  • 1Department of Cardiology, Istanbul University Institute of Cardiology, Istanbul, Turkey.

Echocardiography (Mount Kisco, N.Y.)
|March 5, 2015
PubMed

Insights

Four-dimensional speckle tracking echocardiography (4DSTE) reveals distinct left ventricular (LV) contractility patterns in hypertrophic cardiomyopathy (HCM) patients, showing reduced longitudinal and radial strain with increased circumferential and area strain.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Abnormal left ventricular (LV) mechanics are known in hypertrophic cardiomyopathy (HCM).
  • Previous studies utilized two-dimensional speckle tracking echocardiography (2DSTE) to assess LV deformation.
  • Limited data exists on four-dimensional speckle tracking echocardiography (4DSTE) in HCM patients.

Purpose of the Study:

  • To identify and quantify LV contractility in HCM patients using 4DSTE.
  • To evaluate the utility of 4DSTE in assessing LV deformational mechanics in HCM.

Main Methods:

  • Thirty nonobstructive HCM patients and 20 healthy controls underwent 4DSTE.
  • Measurements included longitudinal, radial, circumferential, and area strains.
  • Peak LV twist was also quantified.

Main Results:

  • HCM patients exhibited significantly lower longitudinal and radial strain compared to controls.
  • HCM patients demonstrated significantly higher circumferential and area strain than controls.
  • Peak LV twist was significantly higher in HCM patients.

Conclusions:

  • 4DSTE reveals reduced longitudinal and radial strain, alongside increased circumferential and area strain in HCM patients.
  • These findings align with previous 2DSTE studies.
  • 4DSTE is a valuable tool for assessing LV deformational mechanics in HCM.
Abstract

Keywords:
echocardiographyfour-dimensionalhypertrophic cardiomyopathyspeckle tracking

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