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Updated: Apr 16, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
A microextraction procedure based on a task-specific ionic liquid for the separation and preconcentration of lead
Asma Saljooqi1,2, Tayebeh Shamspur1, Maryam Mohamadi1,2
1Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran.
Abstract:
First, the extraction and preconcentration of ultratrace amounts of lead(II) ions was performed using microliter volumes of a task-specific ionic liquid. The remarkable properties of ionic liquids were added to the advantages of microextraction procedure. The ionic liquid used was trioctylmethylammonium thiosalicylate, which formed a lead thiolate complex due to the chelating effect of the ortho-positioned carboxylate relative to thiol functionality. So, trioctylmethylammonium thiosalicylate played the roles of both chelating agent and extraction solvent simultaneously. Hence, there is no need to use a ligand. The main parameters affecting the efficiency of the method were investigated and optimized. Under optimized conditions, this approach showed a linear range of 2.0-24.0 ng/mL with a detection limit of 0.0010 ng/mL. The proposed method was applied to the extraction and preconcentration of lead from red lipstick and pine leaves samples prior to electrothermal atomic absorption spectroscopic determination.
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