Related Experiment Video For Cervical sampling
Updated: Apr 16, 2026
Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Adequacy of cervical sampling in hysterectomy specimens for endometrial cancer
Sheeba Syed1, Nick Reed2, David Millan1
1Department of Pathology Laboratory Medicine/FM Building, Southern General Hospital, Glasgow, UK.
Aim:
To determine whether sampling one section, which includes the anterior and posterior cervical lips in hysterectomy specimens, provides the best prospect for detecting stromal invasion in hysterectomy specimens for endometrial cancers.
Methods:
To assess the most likely section in which cervical stromal invasion was identified in 29 cases.
Results:
Cervical stromal invasion was detected in first section in 75.8% cases, whereas 24.1% detected in random sections other than first section.
Conclusion:
Cervical stromal invasion is most likely to be identified in one section taken in the midline, which includes anterior and posterior lips. However, in a significant number of cases, this one section missed invasion, which was detected in other random cervical sections. Therefore, sampling of one block (anterior and posterior) from the cervix is insufficient for detecting cervical stromal invasion for endometrial cancer.
