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Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Responses to Heat and Cold Stress02:45

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Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
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Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
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A link between cold environment and cancer.

Ankit Sharma1, Harphool Kumar Verma, Savitri Joshi

  • 1Department of Biochemistry, Central University of Rajasthan, NH-8, Bandarsindri, Kishangarh, 305817, Ajmer, Rajasthan, India.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
|March 5, 2015
PubMed
Summary
This summary is machine-generated.

Cold environmental temperatures may increase cancer risk. This study found higher cancer mortality rates in colder countries, suggesting temperature impacts tumorigenesis. Further research is needed to understand this link.

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Area of Science:

  • Environmental Science
  • Oncology
  • Epidemiology

Background:

  • Established cancer risk factors include lifestyle choices and genetic predispositions.
  • Environmental factors are increasingly recognized for their role in cancer development.

Purpose of the Study:

  • To investigate the potential association between average annual temperature (AAT) and cancer mortality rate (CMR).
  • To explore environmental temperature as a novel risk factor for tumorigenesis.

Main Methods:

  • Multivariate and univariate analyses were performed on data from 188 countries.
  • Countries were categorized into three temperature zones based on AAT.
  • Cancer mortality rates were correlated with AAT and other lifestyle variables.

Main Results:

  • A significant contribution of AAT to cancer deaths was observed, independent of other factors.
  • Univariate analysis revealed a negative correlation between AAT and CMR.
  • Higher CMR was found in countries with lower AAT (colder climates), particularly those situated away from the Torrid zone.

Conclusions:

  • Cold temperatures may be a contributing factor to increased cancer mortality.
  • Elevated metabolic stress in cold environments could potentially drive higher rates of tumorigenesis.