Related Experiment Video

Updated: Apr 16, 2026

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

2.3K

Hand schuller christian disease: a rare case report with oral manifestation

Ch Lalitha1, M Manjula2, K Srikant3

  • 1Senior Lecturer, Department of Oral Medicine and Radiology, Sri Sai College of Dental Surgery , Vikarabad,Telanagana, India .

Journal of Clinical and Diagnostic Research : JCDR
|March 5, 2015
PubMed

Insights

Langerhan's Cell Histiocytosis (LCH) is a rare disorder involving abnormal Langerhan cell proliferation. This case report details a 6-year-old boy diagnosed with Hand Schuller Christian Disease, a type of LCH, presenting with eye and dental issues.

Area of Science:

  • Histiocytosis
  • Pediatric Pathology
  • Rare Diseases

Background:

  • Langerhan's Cell Histiocytosis (LCH) comprises disorders characterized by abnormal proliferation of Langerhan cells.
  • LCH presents clinically as eosinophilic granuloma, Hand Schuller Christian disease, and Abt-Letterer-Siwe disease.
  • Manifestations occur in both children and adults due to Langerhan cell infiltration.

Observation:

  • A rare case of LCH in a 6-year-old boy is presented.
  • The patient exhibited extraoral exophthalmos of the right eye and oral symptoms including tooth mobility.
  • Typical radiological findings were observed.

Findings:

  • Clinical, radiological, and histopathological examinations confirmed the diagnosis.
  • The patient was diagnosed with Hand Schuller Christian Disease, a specific type of LCH.
  • The case highlights unusual extraoral and oral manifestations.

Implications:

  • This case underscores the diverse clinical presentations of LCH, particularly Hand Schuller Christian Disease.
  • Early diagnosis and recognition of varied symptoms are crucial for effective management.
  • Further research into LCH's varied manifestations can improve patient outcomes.

Keywords:
Hand-schuller-christian diseaseHistiocytosisLangerhan cell

More Related Videos

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies05:42

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

1.8K
Oral Health Assessment by Lay Personnel for Older Adults08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

13.9K

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
869
Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.6K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
1.2K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
951
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
1.2K
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
4.1K