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Related Experiment Video

Updated: Jan 13, 2026

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring

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Maternal migration and autism risk: systematic analysis.

Daina Crafa¹, Nasir Warfa

¹Integrated Program in Neuroscience, Douglas Mental Health University Hospital, McGill University , Montreal, Quebec , Canada.

International Review of Psychiatry (Abingdon, England)

|March 5, 2015

Summary

Autism (AUT) risk is higher in some migrant communities due to maternal stressors and epigenetic factors. Understanding these public health disparities is crucial for supporting affected cultural groups.

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Published on: March 25, 2016

Area of Science:

Developmental Disorders
Neuroscience
Public Health

Background:

Autism (AUT) is a prevalent and incapacitating developmental disorder.
AUT can necessitate lifelong supervised care and incurs significant economic costs.
Ethnicity and migration are increasingly recognized as factors influencing AUT risk.

Purpose of the Study:

To systematically review the prevalence and predictors of AUT.
To focus on maternal migration stressors and epigenetic risk factors in AUT.
To highlight public health needs within specific cultural groups.

Main Methods:

Systematic review of existing literature.
Analysis of prevalence data for AUT in migrant populations.
Investigation of sociobiological and epigenetic factors linked to AUT.

Main Results:

Children from migrant communities, excluding Hispanic children, show a higher risk of AUT.
AUT rates appear elevated in certain migrant groups, potentially linked to epigenetic changes from stress.
Maternal migration stressors and epigenetic factors are significant predictors of AUT.

Conclusions:

Autism Spectrum Disorder (ASD) prevalence is influenced by maternal migration and associated stressors.
Epigenetic changes during pregnancy and delivery may play a role in ASD development.
Addressing public health urgencies and community needs is vital to support at-risk cultural groups.