Related Experiment Videos
Brain-specific expression of transthyretin mRNA as revealed by cDNA cloning from brain
1Department of Biochemistry, School of Pharmaceutical Sciences, Toho University, Chiba, Japan.
FEBS Letters
|November 20, 1989
Abstract:
cDNAs for rat transthyretin mRNA were cloned from a brain cDNA library. Sequencing analyses showed the presence of an additional 5' sequence that had not been reported for the liver mRNA corresponding to the flanking promoter region of the gene. This additional sequence was expressed only in the brain, suggesting the presence of a brain-specific promoter.