Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioreactor Controls-III

Bioreactor Controls-III

Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...

Production of Organic Acids

Production of Organic Acids

Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...

Scale-Up Processes

Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...

Microbes in Food Production

Microbes in Food Production

Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...

Environmental Applications of Microorganisms

Environmental Applications of Microorganisms

Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...

Microbial Bioremediation of Plastics

Microbial Bioremediation of Plastics

Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bioprospecting of Native Efflux Pumps To Enhance Furfural Tolerance in Ethanologenic <i>Escherichia coli</i>.

Applied and environmental microbiology·2019

Same author

Experimental evolution reveals an effective avenue to release catabolite repression via mutations in XylR.

Proceedings of the National Academy of Sciences of the United States of America·2017

Same author

Retinaldehyde dehydrogenase 2 as a molecular adjuvant for enhancement of mucosal immunity during DNA vaccination.

Vaccine·2016

Same author

Rapid Identification of Methicillin-Resistant Staphylococcus aureus (MRSA) by the Vitek MS Saramis system.

Current microbiology·2015

Same author

Polymorphism of IL37 gene as a protective factor for autoimmune thyroid disease.

Journal of molecular endocrinology·2015

Same author

Hepatitis B virus X protein modulates renal tubular epithelial cell-induced T-cell and macrophage responses.

Immunology and cell biology·2015

Search research articles

Related Experiment Video

Updated: Apr 16, 2026

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Published on: October 24, 2016

Engineering Sugar Utilization and Microbial Tolerance toward Lignocellulose Conversion.

Lizbeth M Nieves¹, Larry A Panyon¹, Xuan Wang¹

¹School of Life Sciences, Arizona State University , Tempe, AZ , USA.

Frontiers in Bioengineering and Biotechnology

|March 6, 2015

Summary

This summary is machine-generated.

Synthetic biology enhances lignocellulose conversion for sustainable fuels and chemicals. This review details optimizing biological parts and systems for better sugar utilization and tolerance to fermentation inhibitors from renewable biomass.

Keywords:

furan aldehydes lignocellulose metabolic engineering synthetic biology xylose

More Related Videos

Methods for Facilitating Microbial Growth on Pulp Mill Waste Streams and Characterization of the Biodegradation Potential of Cultured Microbes

Methods for Facilitating Microbial Growth on Pulp Mill Waste Streams and Characterization of the Biodegradation Potential of Cultured Microbes

Published on: December 12, 2013

High-throughput Saccharification Assay for Lignocellulosic Materials

High-throughput Saccharification Assay for Lignocellulosic Materials

Published on: July 3, 2011

Related Experiment Videos

Last Updated: Apr 16, 2026

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Published on: October 24, 2016

Methods for Facilitating Microbial Growth on Pulp Mill Waste Streams and Characterization of the Biodegradation Potential of Cultured Microbes

Methods for Facilitating Microbial Growth on Pulp Mill Waste Streams and Characterization of the Biodegradation Potential of Cultured Microbes

Published on: December 12, 2013

High-throughput Saccharification Assay for Lignocellulosic Materials

High-throughput Saccharification Assay for Lignocellulosic Materials

Published on: July 3, 2011

Area of Science:

Biotechnology
Synthetic Biology
Biochemical Engineering

Background:

Renewable feedstock like lignocellulosic biomass offers a sustainable alternative to petrochemicals for fuel and chemical production.
Fermentation-based processes are key, but challenges remain in efficient lignocellulose conversion.
Synthetic biology presents a promising avenue to address these conversion challenges.

Purpose of the Study:

To review advancements in synthetic biology for improved lignocellulose utilization.
To highlight the identification and optimization of synthetic biological parts.
To discuss integrated biological systems for enhanced biomass conversion.

Main Methods:

Summarizing research on synthetic biological parts for sugar utilization.
Reviewing strategies to increase biocatalyst tolerance to fermentation inhibitors.
Analyzing ongoing efforts and future applications of integrated biological systems.

Main Results:

Synthetic biology tools enable enhanced utilization of lignocellulose-derived sugars.
Optimization of biological parts improves biocatalyst performance.
Integrated systems show potential for efficient biomass conversion.

Conclusions:

Synthetic biology is crucial for overcoming lignocellulose conversion limitations.
Further development of synthetic biological parts and systems is needed.
Future applications promise more sustainable fuel and chemical production from renewable resources.