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Updated: Apr 16, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Troubleshooting in extracorporeal life support
1Department of Surgery and Anaesthesiology, Cardiovascular Research, University Hospital Lausanne, Switzerland.
Abstract:
Since the first clinical use of extracorporeal circulation in the last century by John Gibbon and the first successful mechanical support of the left ventricular function by Forest Dodrill, the progress of techniques and technologies has helped to develop minimised systems for extracorporeal circulatory and respiratory support. However, the fact is that, despite the advanced technologies used for extracorporeal support, successful application in order to be benefit a critically ill population requires highly trained and skilled teams. Application of these highly sophisticated techniques in life-saving situations inside and/or outside the operating room is a procedure with certain pitfalls and dangers. The aim of this review is to provide a short overview of the technical aspects of extracorporeal circulation, with a look at the recent literature and clinical experiences focusing on technical as well surgical considerations regarding the urgent and/or emergent usage of a central as well as peripheral extracorporeal system.
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