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Updated: Apr 16, 2026
![Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62334.jpg&w=3840&q=50)
Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
Published on: February 17, 2022
Clinicoradiologic response of neurologic tuberculous mass lesions in children treated with thalidomide
Ronald van Toorn1, Anne-Marie du Plessis, Hendrik Simon Schaaf
1From the *Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children's Hospital; †Division of Radiodiagnosis, Stellenbosch University and Tygerberg Hospital; ‡Department of Paediatrics, New-Somerset Hospital; and §Department of neuropathology, University of Cape Town, Cape Town, South Africa.
Abstract:
Neurologic tuberculous pseudoabscesses that clinically progress despite conventional antituberculosis therapy may be responsive to adjuvant thalidomide, a potent tumor necrosis factor-α inhibitor. In this study, the addition of thalidomide provided substantial clinical benefit in the majority of patients, and magnetic resonance imaging evolution of lesions from early-stage "T2 bright" with edema to "T2 black" represented a marker of cure.
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