Solitary epibulbar neurofibroma in older adult patients
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Published on: May 26, 2023
Thais Shiota Tanaka1, Victor M Elner, Hakan Demirci
1*Department of Ophthalmology and Vision Sciences, WK Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI; and †Department of Pathology, University of Michigan Medical School, Ann Arbor, MI.
Purpose:
To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis.
Methods:
Case reports and literature review.
Results:
A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circumscribed lesion was present deep to the nasal bulbar conjunctiva. A 60-year-old otherwise healthy man presented with a 6-week history of a subconjunctival growth causing pain and photophobia in his right eye. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circumscribed subconjunctival lesion, causing a delle was present near the nasal limbus. In each case, excisional biopsy was performed and histopathologic study revealed the diagnosis of neurofibroma. In both cases, after 12 months of follow-up, there was no evidence of recurrence or systemic disease.
Conclusions:
Solitary epibulbar neurofibroma in older adult patients without systemic neurofibromatosis is rare but should be considered in the differential diagnosis of epibulbar tumors.
