Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

636
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
636
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

2.2K
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
2.2K
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

859
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
859
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

6.5K
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
6.5K
Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

1.3K
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
1.3K
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

1.2K
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Algorithm-Based Care for Treating Chronic Pancreatitis: A Nationwide Stepped-Wedge Cluster Randomized Controlled Trial.

The American journal of gastroenterology·2026
Same author

GastroNet-5M: A Multicenter Dataset for Developing Foundation Models in Gastrointestinal Endoscopy.

Gastroenterology·2025
Same author

Challenges in Implementing Endoscopic Artificial Intelligence: The Impact of Real-World Imaging Conditions on Barrett's Neoplasia Detection.

United European gastroenterology journal·2025
Same author

Prevalence and associated factors of worry for cancer in patients with a Barrett's esophagus.

Scientific reports·2024
Same author

Development of pancreatic diseases during long-term follow-up after acute pancreatitis: a post-hoc analysis of a prospective multicenter cohort.

Journal of gastroenterology and hepatology·2024
Same author

A deep learning system for detection of early Barrett's neoplasia: a model development and validation study.

The Lancet. Digital health·2023

Related Experiment Video

Updated: Apr 16, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.5K

Diagnosis by endoscopy and advanced imaging.

A Swager1, W L Curvers1, J J Bergman1

  • 1Dept. of Gastroenterology and Hepatology Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands.

Best Practice & Research. Clinical Gastroenterology
|March 7, 2015
PubMed
Summary

High-definition white light endoscopy (HD-WLE) with random biopsies is effective for detecting early neoplasia in Barrett's oesophagus (BO). Advanced imaging techniques offer limited additional benefit in standard surveillance for BO patients.

Keywords:
Advanced imaging techniquesBarrett's oesophagusEarly neoplasiaSurveillance

More Related Videos

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K
Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

19.6K

Related Experiment Videos

Last Updated: Apr 16, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.5K
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K
Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

19.6K

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Oncology

Background:

  • Barrett's oesophagus (BO) surveillance aims to detect early neoplasia.
  • Advanced endoscopic imaging techniques are increasingly used in BO surveillance.

Purpose of the Study:

  • To compare the diagnostic yield of advanced endoscopic imaging techniques versus high-definition white light endoscopy (HD-WLE) with random biopsy analysis in patients with BO.
  • To evaluate the effectiveness of these techniques in detecting early neoplasia.

Main Methods:

  • Comparison of diagnostic accuracy between HD-WLE with random biopsy analysis and advanced imaging modalities (dye-based chromoendoscopy, optical chromoendoscopy, autofluorescence imaging, confocal laser endomicroscopy).
  • Analysis of detection rates for early neoplasia in a cohort of patients with BO.

Main Results:

  • Advanced imaging techniques did not significantly increase the diagnosis of early neoplasia compared to HD-WLE with random biopsy analysis.
  • HD-WLE with random biopsy analysis detects most cases of neoplasia due to the low prevalence of early neoplasia in BO.
  • Advanced techniques may detect additional flat lesions, but these have limited clinical significance after ablation therapy.

Conclusions:

  • HD-WLE with random biopsy analysis is sufficient for standard surveillance of patients with BO.
  • Evaluation and treatment of BO with early-stage neoplasia should be centralized in expert tertiary referral centers.
  • Optical chromoendoscopy can aid in lesion evaluation before resection and in post-ablation follow-up.