Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Menopause01:28

Menopause

5.2K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.2K
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

2.5K
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
2.5K
Bone Disorders01:29

Bone Disorders

8.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.7K
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

342
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
342
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

359
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
359
Hormonal Regulation01:40

Hormonal Regulation

51.0K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
51.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronic Stress Alters Dorsal Bed Nucleus of Stria Terminalis Synaptic Neurotransmission in a Dravet Syndrome Mouse Model.

bioRxiv : the preprint server for biology·2026
Same author

Pre- to Postseason Reliability of Blink Reflex Parameters in Nonconcussed Athletes.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine·2026
Same author

Short-Wavelength Infrared Imaging with Organic Photodetectors Based on Non-Fullerene Acceptors with Detection above 1200 nm.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Changes in the blink reflex after a sport-related concussion: Test-retest reliability of a blink reflexometer in high school athletes.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2025
Same author

Risk of adverse events from medication errors in general and tertiary hospitals: A cross-sectional design.

Contemporary nurse·2025
Same author

Determinants of Harm in Fall Incidents in Hospital Settings With 200 or More Beds in Korea.

Journal of patient safety·2025

Related Experiment Video

Updated: Apr 16, 2026

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
05:32

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Published on: August 11, 2023

2.7K

[Structural equation modeling on healthy menopausal transition].

Eunyoung Hong1, Young Sil Kang2

  • 1Department of Nursing, Koje College, Geoje, Korea.

Journal of Korean Academy of Nursing
|March 7, 2015
PubMed
Summary
This summary is machine-generated.

Self-differentiation and self-efficacy are key factors for healthy menopausal transition in middle-aged women. Nursing interventions should focus on improving these aspects and managing menopausal symptoms.

Keywords:
MenopauseMiddle agedNursing careQuality of lifeSelf efficacy

More Related Videos

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

16.4K
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

13.1K

Related Experiment Videos

Last Updated: Apr 16, 2026

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
05:32

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

Published on: August 11, 2023

2.7K
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

16.4K
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

13.1K

Area of Science:

  • Reproductive Health
  • Psychology
  • Nursing

Background:

  • Menopause significantly impacts middle-aged women's quality of life.
  • Understanding factors influencing healthy menopausal transition is crucial for targeted interventions.

Purpose of the Study:

  • To construct and test a structural equation model for healthy menopausal transition.
  • To identify key variables affecting healthy menopausal transition in middle-aged women.

Main Methods:

  • 276 women aged 45-60 with menopausal symptoms were recruited.
  • Data collected via questionnaires and analyzed using SPSS and AMOS.
  • Structural equation modeling was employed to test the hypothetical model.

Main Results:

  • The model demonstrated good fit indices (GFI=.93, CFI=.92, RMSEA=.05).
  • Self-efficacy, self-differentiation, and menopausal symptoms explained 67.7% of the variance in menopausal transition.
  • Self-differentiation emerged as the most influential factor.

Conclusions:

  • Nursing interventions targeting self-differentiation and self-efficacy are critical for healthy menopausal transition.
  • Interventions should also focus on managing menopausal symptoms.
  • Community-based nursing programs are recommended to facilitate healthy transitions.