L-tyrosine induces synthesis of melanogenesis related proteins

In cultured amelanotic hamster melanoma cells L-tyrosine induces melanogenesis. This induction involves an increase in intracellular concentration of proteins precipitated by polyclonal anti-tyrosinase antibodies, and stimulation of the Vmax of tyrosinase activity. Therefore it is suggested that in hamster melanoma cells L-tyrosine induces synthesis of tyrosinase and melanogenesis related proteins.