Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

60
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
60
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

5.0K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
5.0K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

412
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
412
Antibiotic Selection00:57

Antibiotic Selection

62.3K
Overview
62.3K
Standard Precaution01:26

Standard Precaution

3.5K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
3.5K
Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

155
Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and...
155

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term sustainability of zero central-line associated bloodstream infections is possible with high compliance with care bundle elements.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit·2015
Same author

Evaluation of sludge management alternatives in Istanbul metropolitan area.

Water science and technology : a journal of the International Association on Water Pollution Research·2005
Same author

Train-pedestrian accidents.

European journal of emergency medicine : official journal of the European Society for Emergency Medicine·2000
Same author

[Laparoscopic management of echinococcal cysts of the liver].

Zentralblatt fur Chirurgie·2000
Same author

Emergency department information: does it effect patients' perception and satisfaction about the care given in an emergency department?

European journal of emergency medicine : official journal of the European Society for Emergency Medicine·2000
Same author

Factors effecting mortality in urban vertical free falls: evaluation of 180 cases.

International surgery·1999

Related Experiment Video

Updated: Apr 16, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.6K

Antibiotic stewardship programmes and the surgeon's role.

M Çakmakçi1

  • 1Anadolu Saglik Merkezi, Kocaeli, Turkey.

The Journal of Hospital Infection
|March 7, 2015
PubMed
Summary

Inappropriate antibiotic use causes patient harm and promotes antibiotic resistance. Antibiotic stewardship programs, especially with surgeon engagement, are essential for optimizing antibiotic prescribing and combating resistance.

Keywords:
Antibiotic resistanceAntibiotic stewardshipComplicationsPatient safetyQuality of careSurgery

Related Experiment Videos

Last Updated: Apr 16, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.6K

Area of Science:

  • Infectious Diseases
  • Public Health
  • Surgical Sciences

Background:

  • Inappropriate antibiotic use is prevalent, particularly in surgical settings.
  • This misuse leads to adverse patient outcomes and the proliferation of antibiotic-resistant bacteria.
  • Antibiotic resistance poses a significant global health threat.

Purpose of the Study:

  • To discuss the impact of improper antibiotic usage.
  • To advocate for antibiotic stewardship programs as a solution.
  • To highlight the critical role of surgeons in these programs.

Main Methods:

  • Literature review and expert opinion on antibiotic stewardship.
  • Analysis of the consequences of inappropriate antibiotic prescribing.
  • Discussion of strategies for optimizing antibiotic use in surgical units.

Main Results:

  • Improper antibiotic use results in increased patient morbidity and mortality.
  • The spread of antibiotic resistance is exacerbated by non-judicious prescribing.
  • Antibiotic stewardship programs offer a structured approach to mitigate these issues.

Conclusions:

  • Antibiotic stewardship is the most effective strategy to combat inappropriate antibiotic use and resistance.
  • Active engagement of surgeons is paramount for the successful implementation of stewardship programs.
  • Optimizing antibiotic selection, dosage, route, and duration improves patient outcomes and reduces costs.