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Lack of association between scleroderma and types I and III procollagen gene restriction fragment length
L E Kratz1, J A Boughman, B W Needleman
1Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore 21201.
Arthritis and Rheumatism
|December 1, 1989
Abstract:
Restriction fragment length polymorphisms (RFLPs) in types I and III procollagen genes were studied in 62 scleroderma patients and 138 healthy controls. Allelic frequencies were determined for each RFLP, and comparisons were made between the 2 populations, stratifying them by race when appropriate. No statistically significant differences were observed for the frequencies of any of the RFLPs studied.