Exacerbation of adenomyosis symptomatology by estrogen-progestin therapy: a case report and histopathological observations
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1Department of Pathology, Columbia Hospital for Women Medical Center, Washington, D.C.
International Journal of Fertility
|November 1, 1989
Abstract:
The present case report illustrates the hormonal sensitivity of adenomyosis. Administration of an estrogen-progestin combination for what was felt to be symptomatic endometriosis resulted in exacerbation of symptoms and growth of adenomyomas. Histopathologic examination of the hysterectomy specimen revealed a pattern of decidualization previously unreported, but consistent with current theories of experimental in vivo and in vitro decidua formation.
Keywords:
AmericasBiologyCase StudiesContraceptionContraceptive Agents, Estrogen--therapeutic useContraceptive Agents, Female--therapeutic useContraceptive Agents, Progestin--therapeutic useContraceptive Agents--therapeutic useCytologic EffectsDecidual Cell ReactionDeveloped CountriesDiseasesDistrict Of ColumbiaEthynodiol Diacetate--therapeutic useFamily PlanningGenitaliaGenitalia, FemaleGynecologic SurgeryHysterectomyLaparotomyMestranol--therapeutic useMyometrial EffectsMyometriumNorth AmericaNorthern AmericaPainPhysiologyResearch MethodologySigns And SymptomsStudiesSurgeryTreatmentUnited StatesUrogenital SurgeryUrogenital SystemUterus