Related Experiment Videos
Use of cyclosporin in psoriasis
J D Bos1, M M Meinardi, T van Joost
1Department of Dermatology, University of Amsterdam, The Netherlands.
Lancet (London, England)
|December 23, 1989
Abstract:
In the treatment of severe psoriasis, cyclosporin may achieve improvement or remission at low doses, but relapse usually occurs on withdrawal of treatment. An initial dose of 3 mg/kg per day is recommended. Complete remission should not be the objective, and the role of long-term maintenance cyclosporin therapy is uncertain because of potential side-effects--especially nephrotoxicity, hypertension, and a predisposition to malignancy. Guidelines are proposed for the assessment of such treatment.