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Related Concept Videos

Vaccines01:21

Vaccines

62
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
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Vaccinations01:51

Vaccinations

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Overview
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Vaccine Production01:23

Vaccine Production

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Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
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Active versus Passive Immunity01:31

Active versus Passive Immunity

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
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Vaccines, our shared responsibility.

Sonia Pagliusi1, Rishabh Jain2, Rajinder Kumar Suri2

  • 1DCVMN International, Route de Crassier 7, 1262 Nyon, Switzerland.

Vaccine
|March 10, 2015
PubMed
Summary
This summary is machine-generated.

The Developing Countries Vaccine Manufacturers' Network (DCVMN) meeting focused on global vaccine development and supply. Key discussions included overcoming regulatory hurdles and fostering collaborations for affordable vaccines against infectious diseases.

Keywords:
CollaborationDeveloping countriesImmunizationInnovationVaccines

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Area of Science:

  • Global Health
  • Vaccinology
  • Infectious Disease Prevention

Background:

  • The Developing Countries Vaccine Manufacturers' Network (DCVMN) convened its 15th annual meeting in New Delhi, India, with over 240 delegates from 36 countries.
  • The meeting aimed to advance the shared goal of preventing mortality and morbidity from infectious diseases through collaborative efforts.

Framework:

  • Discussions centered on three core themes: regulatory challenges in developing nations, the importance of global partnerships for vaccine investment and supply chain stability, and innovation in vaccine development.
  • Specific focus areas included novel vaccines for diseases like dengue, Chikungunya, typhoid, and EV71, alongside advancements in vaccine delivery technologies such as needle-free systems.

Implementation:

  • The meeting highlighted successes in polio eradication in South East Asia and addressed future challenges in vaccine supply for measles-rubella immunization.
  • Emphasis was placed on innovative solutions and technologies to achieve global immunization targets.

Implications:

  • Participants reaffirmed their commitment to the Decade of Vaccines initiative, underscoring the collective responsibility to eliminate vaccine-preventable diseases.
  • The outcomes support enhanced communication, strategic partnerships, and technological innovation to ensure access to affordable, suitable vaccines worldwide.