[3-substituted 1,2-benzisoxazole and their neuroleptic activity]

The authors report the synthesis of two new derivatives of 3-substituted 1,2-benzisoxazole. The new molecules (P-1368, P-1370), evaluated in many pharmacological C.N.S. tests, show interesting neuroleptic activity but inferior to those of haloperidol and chlorpromazine.