Machine learning applications in cancer prognosis and prediction
Konstantina Kourou1, Themis P Exarchos2, Konstantinos P Exarchos1
1Unit of Medical Technology and Intelligent Information Systems, Dept. of Materials Science and Engineering, University of Ioannina, Ioannina, Greece.
Machine learning (ML) methods are increasingly used in cancer research to predict patient outcomes and model disease progression. This review highlights recent ML applications for cancer risk assessment and clinical decision-making.
Area of Science:
- Oncology
- Bioinformatics
- Computational Biology
Background:
- Cancer is a heterogeneous disease requiring early diagnosis and prognosis for effective patient management.
- Classifying cancer patients into risk groups is crucial for personalized treatment strategies.
- Machine learning (ML) methods offer powerful tools for analyzing complex cancer datasets.
Purpose of the Study:
- To review recent machine learning (ML) approaches applied to cancer progression modeling.
- To highlight ML techniques used for predicting cancer risk and patient outcomes.
- To provide an overview of current trends in ML for cancer research.
Main Methods:
- Review of recent publications employing supervised ML techniques.
- Analysis of studies utilizing various input features and data samples for predictive modeling.
- Focus on ML methods such as Artificial Neural Networks (ANNs), Bayesian Networks (BNs), Support Vector Machines (SVMs), and Decision Trees (DTs).
Main Results:
- ML methods have demonstrated effectiveness in developing accurate predictive models for cancer.
- Key features from complex datasets can be identified using ML tools, aiding in understanding cancer progression.
- Various ML techniques are being applied to model cancer risk and patient outcomes.
Conclusions:
- ML methods show significant potential to improve the understanding and clinical management of cancer.
- Further validation is necessary for the widespread adoption of ML in clinical practice.
- The application of ML in cancer research is a growing trend with promising future implications.
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