Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same author

Spectrum of Dystonia in Spinocerebellar Ataxia.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same author

Dystonia and Tremor.

Seminars in neurology·2026
Same author

Understanding Sociocultural Factors Shaping Married Men's Vasectomy Decisions: A Qualitative Study in Bihar.

Cureus·2026
Same author

Tremor.

Seminars in neurology·2026
Same author

Chromatin rewiring of β-globin and MYC enhancers by TGF-β1 drives defective erythropoiesis.

Nature communications·2026
Same journal

A Life in Service of Neuroscience, Healing, and Teaching.

Neurology India·2026
Same journal

IN MEMORIAM.

Neurology India·2026
Same journal

Extensive Diffusion Restriction of White Matter, Midbrain, and Basal ganglia in a Neonate with Refractory Hypoglycemic Seizures.

Neurology India·2026
Same journal

CHD2-Related Developmental Epileptic Encephalopathy and Angelman Syndrome in a Girl: A Double Jeopardy.

Neurology India·2026
Same journal

Cerebral Schistosomiasis Mimicking Multiple Intracranial Metastases.

Neurology India·2026
Same journal

Extrusion of Spinal Implants Through the Overlying Skin: A Rare Epiphenomenon of Metal Allergy.

Neurology India·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.6K

Deep brain stimulation: current status.

Sanjay Pandey1, Neelav Sarma

  • 1Department of Neurology, Govind Ballabh Pant Postgraduate Institute of Medical Education and Research, New Delhi, India.

Neurology India
|March 10, 2015
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) is increasingly used for neurological and psychiatric conditions like Parkinson's disease and depression. This review covers current applications, investigational uses, and potential complications of this advanced neuromodulation technique.

More Related Videos

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.5K
An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation
12:26

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

Published on: June 2, 2018

8.4K

Related Experiment Videos

Last Updated: Apr 16, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.6K
Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.5K
An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation
12:26

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

Published on: June 2, 2018

8.4K

Area of Science:

  • Neurology
  • Neurosurgery
  • Psychiatry

Background:

  • Deep brain stimulation (DBS) applications have significantly expanded over the past two decades.
  • Established indications include Parkinson's disease, essential tremors, primary dystonia, and medically refractory seizures.
  • Investigational uses extend to Tourette's syndrome, tardive dyskinesia, obsessive-compulsive disorder, and depression.

Purpose of the Study:

  • To provide a comprehensive overview of the current status of DBS.
  • To highlight recent advances in DBS technology and application.
  • To discuss the spectrum of indications and associated complications.

Main Methods:

  • Review of current literature on deep brain stimulation.
  • Analysis of established and investigational applications across neurological and psychiatric disorders.
  • Examination of surgical, device-related, and stimulation-related complications.

Main Results:

  • DBS is a well-established treatment for several movement disorders and epilepsy.
  • Emerging applications show promise in psychiatric conditions like OCD and depression.
  • Complications are primarily associated with the surgical procedure and device management.

Conclusions:

  • Deep brain stimulation represents a rapidly evolving therapeutic modality in neuroscience.
  • Continued research is essential to refine techniques and expand the utility of DBS.
  • Understanding potential risks is crucial for patient selection and management.