Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

5.6K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.6K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

412
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
412
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

60
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
60

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultraviolet irradiation-responsive dynamic ultralong organic phosphorescence in polymeric systems.

Nature communications·2021
Same author

Wavelength beam-combining of terahertz quantum-cascade laser arrays.

Optics letters·2021
Same author

Ultrafast light field tomography for snapshot transient and non-line-of-sight imaging.

Nature communications·2021
Same author

Supercapsular percutaneously-assisted total hip (SuperPath) versus mini-incision posterolateral total hip arthroplasty for hip osteoarthritis: a prospective randomized controlled trial.

Annals of translational medicine·2021
Same author

Association of apolipoproteins A1 and B with type 2 diabetes and fasting blood glucose: a cross-sectional study.

BMC endocrine disorders·2021
Same author

Transgluteal versus prone approach to extracorporeal shockwave lithotripsy for patients with distal ureteral stones: A systematic review and meta-analysis.

Asian journal of surgery·2021

Related Experiment Video

Updated: Apr 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

34.4K

Antibiotics may not decrease prostate-specific antigen levels or prevent unnecessary prostate biopsy in patients with

Lu Yang1, Yuchun Zhu1, Zhuang Tang1

  • 1Department of Urology, West China Hospital, Sichuan University, Chengdu, China.

Urologic Oncology
|March 11, 2015
PubMed
Summary
This summary is machine-generated.

Empiric antibiotics did not significantly lower prostate-specific antigen (PSA) levels or reduce the need for unnecessary prostate biopsies (PBs) in patients with moderately elevated PSA. Further research is needed to explore alternative strategies for managing elevated PSA levels.

Keywords:
AntibioticProstate biopsyProstate cancerProstate-specific antigenRandomized controlled trial

More Related Videos

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
13:19

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

17.3K
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

2.0K

Related Experiment Videos

Last Updated: Apr 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

34.4K
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
13:19

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

17.3K
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

2.0K

Area of Science:

  • Urology
  • Pharmacology

Background:

  • Elevated prostate-specific antigen (PSA) levels often prompt prostate biopsies (PBs) to rule out cancer.
  • Empiric antibiotic treatment is sometimes used with the aim of reducing PSA levels and potentially avoiding unnecessary PBs.

Purpose of the Study:

  • To systematically evaluate the efficacy of empiric antibiotics in decreasing PSA levels.
  • To determine if empiric antibiotic use can help avoid unnecessary prostate biopsies.

Main Methods:

  • A systematic review and meta-analysis of 6 randomized controlled trials (RCTs) involving 656 patients.
  • Included studies compared empiric antibiotics with placebo or no treatment in patients with moderately increased PSA levels.
  • Statistical analysis was performed using Cochrane Collaboration Review Manager software.

Main Results:

  • No significant differences were observed between antibiotic and control groups in post-treatment PSA levels, decreased PSA levels, PSA density, or free/total PSA percentage.
  • The number of patients with responsive PSA and positive prostate cancer rates also showed no significant differences.
  • A significant net decrease in PSA was observed in the antibiotic group compared to the control group (MD = 1.44, P = 0.0001).

Conclusions:

  • Empiric antibiotic administration does not appear to significantly lower PSA levels.
  • The use of empiric antibiotics is unlikely to be effective in avoiding unnecessary prostate biopsies.