Electro-acupuncture modifies humoral immune response in the rat

The immunomodulating properties of "Shangqiu" (LP-5), "Ququan" (H-8), and "Rangu" (R-2) points were studied in several experiments performed on male Wister rats treated bilaterally by acupuncture (A) or electro-acupuncture (EA). On the stimulation day 3, the sheep-red-blood cells (SRBC) antigen was injected intraperitoneally and four days later, the immunological tests (plaque forming cells-PFC, direct microhemagglutination) were performed. Also, the relative weights of lymphoid organs (spleen and thymus) and adrenal gland were derived after sacrifice. The results obtained suggest pronounced immunomodulating properties of 200 Hz cathodal current stimulation at H-8 point. The immunosuppression observed reflected in a decreased number of PFC and reduced relative weights of adrenal gland revealed in all A- or EA-treated groups.