Initial experience of use of tolvaptan in critically ill patients with fluid overload
J Ruiz-Ramos1, M Gordon, M A Cortes
1Intensive Care Unit, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
What Is Known And Objective:
Positive volume balance is related with high mortality in critically ill patients. We describe our experience in the use of tolvaptan in patients with fluid overload.
Case Summary:
Six patients in the recovery phase from septic shock were included. All patients achieved an increase in diuresis after the first day, with a median fluid balance variation of -2362 (-485 to -3447) mL. At the end of treatment, median fluid balance variation was -9080 (-26,784 to -4395) mL.
What Is New And Conclusion:
Tolvaptan could be an option in critically ill patients with fluid overload and resistant or not treatable with conventional diuretics.
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