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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

Updated: Apr 16, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Improving red cell transfusion in the elective surgical setting: an improvement collaborative with evaluation.

B T Harrison1, J Chen, C Der Vartanian

  • 1Clinical Excellence Commission, Sydney, NSW, Australia.

Vox Sanguinis
|March 11, 2015
PubMed
Summary

The Blood Watch (BW) program significantly reduced inappropriate red cell transfusions in New South Wales hospitals by 27.4%. This initiative also achieved substantial annual cost savings exceeding $8.5 million.

Keywords:
clinical practice improvementcollaborative improvementpatient blood managementpostoperative transfusionred blood cell transfusion

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Area of Science:

  • Healthcare Quality Improvement
  • Health Services Research
  • Patient Safety

Background:

  • Approximately 30% of red cell transfusions in stable adult patients were inappropriate in NSW hospitals.
  • The Australian government spent $878.8 million on blood products and plasma in 2009-2010.
  • The Clinical Excellence Commission (CEC) initiated the Blood Watch (BW) program to address transfusion overuse.

Purpose of the Study:

  • To evaluate the effectiveness of the BW program in reducing inappropriate red cell transfusions.
  • To estimate the potential cost savings associated with the BW program.
  • To assess the impact of BW across five elective surgical groups.

Main Methods:

  • Utilized deterministic linkage of four administrative databases to develop process and outcome indicators.
  • Employed three-level logistic and linear regression to analyze trends in indicators.
  • Applied quadratic regression modeling to estimate avoided red cell transfusions.

Main Results:

  • A 27.4% reduction in blood usage was observed following the BW program's implementation.
  • Reductions in blood usage were consistent across all five studied elective surgical groups.
  • The program generated annual cost savings exceeding $8.5 million.

Conclusions:

  • The BW program, utilizing collaborative improvement methods at scale, significantly decreased blood usage.
  • Consistent reductions in transfusion rates were achieved across diverse surgical patient groups.
  • The initiative demonstrated significant cost-saving benefits for the healthcare system.