Related Experiment Video
Updated: Apr 16, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
Statistical analysis of amino acids in the vicinity of carbohydrate residues performed by GlyVicinity
Miguel A Rojas-Macias1, Thomas Lütteke
1Institute of Veterinary Physiology and Biochemistry, Justus-Liebig-University Giessen, Frankfurter Str. 100, Giessen, 35392, Germany, Miguel.Rojas@vetmed.uni-giessen.de.
Abstract:
Protein-carbohydrate interactions are involved in various essential biological events. 3D structural data from the Protein Data Bank (PDB) can help to understand the molecular basis of the specificity of carbohydrate recognition by proteins. Such interactions can be analyzed statistically using GlyVicinity. This chapter exemplifies the usage of this tool to find information on the frequency of the occurrence of specific amino acids in the vicinity of individual carbohydrate residues and to analyze the type of interacting atoms and their spatial distribution around the glycans.
Related Concept Videos
Protein Glycosylation
Glycosylation occurs in...
Amino acids
Chemistry of Carbohydrates
Chemistry of Carbohydrates
Chemistry of Carbohydrates
Mass Spectrometry of Amines

