Related Experiment Video
Updated: Aug 18, 2026

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
Published on: March 8, 2017
[Is there a drug therapy for sero-mucotympanum?]
1HNO-Klinik im Klinikum Ludwigshafen.
Abstract:
A critical review of the literature (including the authors' own randomized double-blinded studies) does not support the widespread use of drugs for treatment of otitis media with effusion (secretory otitis media).--Neither mucolytic agents, nor decongestants, nor antihistamines have any favourable effect on the course of the disease. Success with steroids or antibiotic agents in selected cases is very limited.
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