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Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

Jimmy F P Berbée1, Mariëtte R Boon1, P Padmini S J Khedoe2

  • 11] Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands [2] Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.

Nature Communications
|March 11, 2015
PubMed
Summary

Activating brown adipose tissue (BAT) lowers cholesterol and triglycerides, protecting against atherosclerosis. This occurs via enhanced fatty acid uptake into BAT and improved hepatic clearance of cholesterol-rich remnants.

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