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Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori
Masatoshi Iga1, Hiroshi Kataoka
1a Department of Integrated Biosciences, Graduate School of Frontier Sciences , The University of Tokyo , Chiba , Japan.
Abstract:
The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R (BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31 was predominantly expressed in the central nervous system and midgut.
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