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Clinical spectrum of Treacher Collins syndrome
Divya Mehrotra1, Mahdi Hasan2, Rahul Pandey3
1Professor, Department of Anatomy, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
Abstract:
Treacher Collins syndrome (TCS) is the most common of the human mandibulofacial dysostosis disorders. It is an autosomal-dominant disorder of the craniofacial development occurring between the fifth and the eighth weeks of embryonic development with an incidence of 1/50,000 live births, range between 1-40,000 and 1-70,000. We present here the various clinical, radiographical and other diagnostic findings of the TCS to correlate the clinical assessment with the diagnostic imaging and review the various investigations and management options being carried out to improve their facial deformity.
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