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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

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Role of stem cells in tooth bioengineering.

Kamleshwar Singh¹, Niraj Mishra¹, Lakshya Kumar²

¹Assistant Professor, Department of Prosthodontics and Dental Material Sciences, Faculty of Dental Sciences, CSM Medical University, Lucknow, Uttar Pradesh, India.

Journal of Oral Biology and Craniofacial Research

|March 11, 2015

Summary

This review explores stem cell sources for laboratory-created teeth, focusing on dentin and enamel formation. It synthesizes research from 1970-2012 on stem cells in dentistry.

Keywords:

Ameloblasts dentin odontoblast stem cells

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Last Updated: Apr 16, 2026

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

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Published on: April 13, 2022

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

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Use of Trowell-Type Organ Culture to Study Regulation of Dental Stem Cells

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Published on: July 8, 2021

Area of Science:

Biomaterials Science
Regenerative Medicine
Developmental Biology

Background:

Tooth regeneration in vitro requires coordinated cellular and molecular events.
Formation of dentin and enamel is crucial for functional tooth development.
Stem cells are key to achieving laboratory-based tooth creation.

Purpose of the Study:

To review and identify diverse stem cell sources utilized for in vitro tooth engineering.
To consolidate findings on stem cell applications in dental research.
To provide an overview of stem cell-based tooth development research.

Main Methods:

Literature search of Medline database from 1970 to 2012.
Inclusion of English language publications only.
Keywords: 'stem cells and dentistry,' 'stem cells and odontoblast,' 'stem cells and dentin,' 'stem cells and ameloblasts.'

Main Results:

Identified various stem cell populations investigated for tooth regeneration.
Highlighted the role of stem cells in dentin and enamel formation.
Summarized the progress in in vitro tooth engineering using stem cells.

Conclusions:

Stem cell manipulation is fundamental for laboratory tooth creation.
Diverse stem cell sources show potential for regenerating tooth-specific hard tissues.
Further research into stem cell synergy is vital for successful dental applications.