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Related Experiment Video

Updated: Apr 16, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

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Transaortic TAVI Is a Valid Alternative to Transapical Approach.

Katie E O' Sullivan1, Eoghan T Hurley, Ricardo Segurado

  • 1The Heart Team, Mater Private Hospital, Dublin, Ireland.

Journal of Cardiac Surgery
|March 11, 2015
PubMed
Summary

Transcatheter aortic valve implantation (TAVI) via transaortic (TAo) and transapical (TA) approaches show similar outcomes. This meta-analysis found no significant differences in mortality, success rates, or complications for TAo versus TA TAVI.

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Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Transcatheter aortic valve implantation (TAVI) offers multiple anatomical access routes.
  • Patient characteristics and operator preference influence the choice between transaortic (TAo) and transapical (TA) TAVI approaches.

Purpose of the Study:

  • To compare procedural outcomes between TAo and TA TAVI.
  • To determine if significant differences exist in key clinical endpoints between these two TAVI access methods.

Main Methods:

  • Systematic review and meta-analysis of published literature.
  • Inclusion of studies reporting outcomes for TAo and TA TAVI procedures.
  • Comparative analysis of procedural success, mortality, and complication rates.

Main Results:

  • Analysis of 10 studies involving 1736 patients (193 TAo, 1543 TA).
  • No significant differences observed in 30-day mortality (9.4% TAo vs. 10.4% TA).
  • Equivalent rates for procedural success, stroke/TIA, major bleeding, pacemaker insertion, and paravalvular regurgitation between TAo and TA approaches.

Conclusions:

  • Transaortic and transapical TAVI approaches demonstrate comparable safety and efficacy.
  • No significant disparities in 30-day mortality, procedural success, or major adverse events.
  • Optimal TAVI access selection should be individualized based on patient and procedural factors.