Related Experiment Video
Updated: Apr 16, 2026

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
Published on: October 16, 2014
Perioperative risk factors for surgical site infection in tibial tuberosity advancement: 224 stifles
1Ignacio Calvo, DECVS, Fitzpatrick Referrals, Halfway Lane, Eashing, Godalming,, Surrey GU7 2QQ, United Kingdom,
Objective:
To examine perioperative factors affecting surgical site infection (SSI) rate following tibial tuberosity advancement (TTA).
Study Design:
Retrospective case series.
Sample Population:
224 stifles in 186 dogs.
Methods:
Medical records of dogs that underwent TTA in a single institution were reviewed. Information on signalment, anaesthetic and surgical parameters, as well as occurrence of SSI was recorded. Dogs were followed for a minimum of three months postoperatively. The association between perioperative factors and SSI was assessed using Chi-squared tests and binary logistic regression.
Results:
The prevalence of SSI was 5.3% (12/224 TTA). Surgical time (p = 0.02) and anaesthesia time (p = 0.03) were significantly associated with SSI. For every minute increase in surgical time and anaesthesia time, the likelihood of developing SSI increased by seven percent and four percent respectively. The use of postoperative antimicrobial therapy was not significantly associated with lower SSI (p = 0.719). Implants were removed in 1.3% of cases (3/224 TTA).
Conclusions:
The findings of this study suggest that increased surgical and anaesthesia times are significant risk factors for SSI in TTA, and that there is no evidence that postoperative prophylactic antimicrobial therapy is associated with SSI rate.
More Related Videos
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

