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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing

Adriana Ordóñez1, Juan Pérez1, Lu Tan1

  • 1*Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain; Wolfson Institute for Biomedical Research, University College London, London, United Kingdom; and Department of Biology and Biotechnologies, "Charles Darwin," and Pasteur Institute, Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|March 12, 2015
PubMed

Keywords:
liver diseasemonoclonal antibodyscFv intrabodyserpin polymer

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